en عمومى General مروری Review article <div style="border-bottom:solid windowtext 1.0pt; border-top:solid windowtext 1.0pt; border-left:none; border-right:none; padding:1.0pt 0in 1.0pt 0in"><span style="font-size:12pt"><span style="unicode-bidi:embed"><span new="" roman="" style="font-family:" times=""><b><span style="font-size:11.0pt">Background and Aims: </span></b><span style="font-size:11.0pt">Viruses manipulate intracellular organelles such as mitochondria, endoplasmic reticulum, cytoskeleton, and lipid droplets to facilitate their own replication. In response, host cells initiate antiviral defenses and reorganize these organelles to combat infection. Mitochondria are a primary target in this process, as viral proteins exploit them to inhibit the host&#39;s antiviral mechanisms. In plants, viral manipulation of mitochondria can disrupt energy production, impacting overall plant health. Similarly, in insects, which serve as crucial vectors for many plant viruses, viral interactions can alter mitochondrial function, affecting both vector competence and the dynamics of disease transmission. The intricate relationship between viruses and mitochondrial dynamics highlights the complexity of host-virus interactions across various biological systems. This paper explores mitochondrial communication with viral infections in mammals, insects, and plants.</span></span></span></span></div> <br> &nbsp; Eukaryotic cells, Mitochondria, Viral infection 33 42 http://journal.isv.org.ir/browse.php?a_code=A-10-367-1&slc_lang=en&sid=1 Mohammadreza Rezapanah rezapana@yahoo.com 10031947532846008023 10031947532846008023 No Iranian Research Institute of Plant Protection (IRIPP), Agricultural Research Education and Extension Organization (AREEO), Tehran 1985713133, Iran Vahideh Hamidi Sofiani vahideh.hamidi@ymail.com 10031947532846008024 10031947532846008024 No Department of Microbiology, Faculty of Medicine, Golestan University of Medical Science, Gorgan, Iran. Malihe Naderi malihenaderi500@yahoo.com 10031947532846008025 10031947532846008025 No Hiroshima Institute of Life Sciences,7-21, Nishi Asahi-Machi, Minami-ku, Hiroshima-shi, Hiroshima,734-0002 Japan Arefeh Ebrahimian Shiadeh viro.science90@gmail.com 10031947532846008026 10031947532846008026 No Department of Microbiology, Faculty of Medicine, Golestan University of Medical Science, Gorgan, Iran. Behnam Baghdadi Behnamamirba@gmail.com 10031947532846008027 10031947532846008027 No Department of Biology, Arts and Science Faculty, Eastern Mediterranean University, Turkey. Iliad Moradi eiliad84@gmail.com 10031947532846008028 10031947532846008028 No Department of Laboratory Sciences, School of Allied Medical Sciences, Iran University of Medical Sciences, Tehran, Iran Mohammadreza Kalani kalanimr@yahoo.com 10031947532846008029 10031947532846008029 No School of Cell and Molecular Biology, University of Illinois at Urbana-Champaign, Urbana, United States Abdolvahab Moradi abmoradi@gmail.com 10031947532846008030 10031947532846008030 Yes Department of Microbiology, Faculty of Medicine, Golestan University of Medical Science, Gorgan, Iran