:: Volume 10, Issue 2 And 3 (9-2016) ::
Iran J Virol 2016, 10(2 And 3): 7-12 Back to browse issues page
Sero-Epidemiology of Hepatitis E Infections in patients with chronic Hepatitis C virus infection in Jahrom, Southern Iran
Hadi Fazel, Enayatollah Shadmand, Rasoul Baharlou, Mohammad Reza Shokouh, Mohammad Ali Hashemi Seyed, Mohammad Farahmand, Abbas Ahmadi Vasmehjani, Kaveh Sadeghi
Virology Department, School of Public Health, Tehran University of Medical Sciences, Tehran, IR Iran
Abstract:   (2511 Views)
Background and Aims: Co-infection of hepatitis E virus (HEV) in chronic hepatitis C virus (HCV) infected patients can develop and increase liver disease and hepatic complications in the world. The purpose of this study was to assess the prevalence of HEV infection in patients suffering from chronic HCV infection.
Materials and Methods: Cross-sectional study testing anti-HEV antibodies in serum samples belonged to 53 chronic HCV infected patients were evaluated. Demographic and clinical data such as liver function tests and enzymes level were prospectively collected on each patient with chronic HCV infection.
Results: There were 5 HEV infected patients IgG positive among the 53 chronic HCV infected patients. These patients had an alanine aminotransferase (ALT) level twice the upper level about of the 48 HEV negative patients (p<0.0001).
Conclusions: Prevalence of HEV sero-positivity patients with HCV co-infection patients was 9.4%. Our results suggest that HEV screening should be implemented in HCV-infected patients with cancer.
Keywords: Hepatitis E, Sero-epidemiology, Hepatitis C
Full-Text [PDF 201 kb]   (363 Downloads)    
Type of Study: Original article | Subject: General
Received: 2017/04/9 | Accepted: 2017/07/29 | Published: 2017/07/29

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Volume 10, Issue 2 And 3 (9-2016) Back to browse issues page