en عمومى General پژوهشي Original article <div style="border-style: solid none border-top-color: windowtext border-top-width: 1pt border-bottom-color: windowtext border-bottom-width: 1pt padding: 1pt 0in"> <p class="MsoNormal" style="border: none padding: 0in"><b>Background and Aims:</b> Recently, a novel DNA virus was isolated from the serum of a patient with post-transfusion non A-G hepatitis and named TT virus. The aim of this study was to determine the prevalence TT virus among cirrhotic patients due to hepatitis B & C in infection <st2:place w:st="on">Ahwaz</st2:place>.<!--stripped--><!--stripped--></p> <p class="MsoNormal" style="border: none padding: 0in"><b>Methods: </b>The prevalence of TTV infection was studied in 41 patients with liver cirrhosis. TTV DNA was detected by semi-nested PCR. The plasma samples were tested for marker hepatitis B & C by <st1:givenname w:st="on">ELISA</st1:givenname> test.<!--stripped--><!--stripped--></p> <p class="MsoNormal" style="border: none padding: 0in"><b>Results:</b> TT virus was detected in 17(41.46%) of the 41 patients with cirrhotic liver disease. There were no significant difference between the subject TTV DNA in relation to sex and age. TTV positivity in cirrhotic patient infected with hepatitis B (52.9%) was higher than in similar patients infected with hepatitis C (47.1%).<!--stripped--><!--stripped--></p> </div> <b><span style="font-size: 12pt font-family: 'Times New Roman', serif">Conclusion:</span></b><span style="font-size: 12pt font-family: 'Times New Roman', serif"> TTV infection was highly prevalence in patient with cirrhotic hepatitis, especially in those with hepatitis B virus infection.</span> Transfusion Transmitted Virus, hepatitis B virus, hepatitis C virus, Liver cirrhosis 29 33 http://journal.isv.org.ir/browse.php?a_code=A-10-1-6&slc_lang=en&sid=1 A Fateh 10031947532846002516 10031947532846002516 No Department of medical virology Ahwaz school of medicine, Ahwaz, Iran M Makvandi manoochehrmakvandi@yahoo.com 10031947532846002517 10031947532846002517 Yes Department of medical virology Ahwaz school of medicine, Ahwaz, Iran A Samarbafzadeh 10031947532846002518 10031947532846002518 No Department of medical virology Ahwaz school of medicine, Ahwaz, Iran H Mollaie 10031947532846002519 10031947532846002519 No Department of medical virology Ahwaz school of medicine, Ahwaz, Iran F Jahanbakhsh 10031947532846002520 10031947532846002520 No Department of medical virology Ahwaz school of medicine, Ahwaz, Iran R Fateh 10031947532846002521 10031947532846002521 No Department of medical virology Ahwaz school of medicine, Ahwaz, Iran