en عمومى General پژوهشي Original article <div> <p><strong>Background and Aims:</strong> Rotaviruses are the main cause of gastroenteritis in the young of human and a variety of animals in the world. Rotavirus G6 and G10 are the most prevalent genotypes in cattle worldwide, but are also found in human with possible origination from animals.</p> <p><strong>Materials and Methods:</strong> In this work, we have detected the G6 and G10 genotypes of bovine rotaviruses isolated from diarrheic calves in Tehran province by RT-PCR. The amplified VP7 genes were cloned, sequenced and compared to the sequences deposited in the GenBank database from the world.</p> <p><strong>Results:</strong> The phylogenetic analysis showed that the Iranian G6 and G10 genotypes are most identical to the genotypes from Ireland (>98.6%&nbsp; amino acid homology) and Canada (>97.3% amino acid homology), respectively.</p> <p><strong>Conclusion: </strong>This high similarity between the Iranian sequences and those from the far countries may suggest that the virus can be spread in a wide geographic region possibly by animal transportation.</p> </div> Bovine rotaviruses, VP7 molecular analysis, Iran 13 18 http://journal.isv.org.ir/browse.php?a_code=A-10-43-8&slc_lang=en&sid=1 H Fani 10031947532846003336 10031947532846003336 No Msc Student, Razi Vaccine & Serum Research Institute, Karaj, Iran M Bakhshesh 10031947532846003337 10031947532846003337 Yes Animal Virology Department, Research and Diagnosis, Razi Vaccine & Serum Research Institute, Karaj, Iran F Pourasgari 10031947532846003338 10031947532846003338 No Department of Biotechnology, Research and Diagnosis, Razi Vaccine & Serum Research Institute, Karaj, Iran Z Sadigh 10031947532846003339 10031947532846003339 No Department of Human Viral Vaccine, Research and Production, Razi Vaccine & Serum Research Institute, Karaj, Iran