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Prevalence of Human Coronaviruses NL63, HKU1, 229E, OC43, MERS, and SARS-CoV-2 among Hospitalized Patients with Acute Respiratory Infection in Tehran
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چکیده: (352 مشاهده) |
| Abstract
Background and Aims: Coronaviruses cause upper respiratory ailments and sporadically lower tract sickness in vulnerable populations. This study examined the prevalence of six human coronaviruses, including severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), OC43, 229E, HKU1, NL63, and Middle East respiratory syndrome coronavirus (MERS-CoV) during the 2019 pandemic caused by SARS-CoV-2 in Tehran, Iran.
Material and methods: Specimens were collected from 204 adult patients with acute respiratory illness. The specimens were examined for the presence of six human coronaviruses using consensus and subtype-specific Real-time reverse-transcription polymerase chain reaction (PCR) assays. The demographic and clinical characteristics associated with coronavirus infection were examined retrospectively.
Results: Coronaviruses were identified in 204 adult patients. The gender ratio was 104/100 male and female, respectively. HCoV-229E, HCoV-NL63, HCoV-OC43, HCoV-HKU1, MERS-CoV, and SARS-CoV-2 were detected in 0.5%, 1.0%, 4.0%, 7.4%, 0.0%, and 22.5% of patients, respectively. The acute clinical features were similar across subtypes. There was no report of fatality incidence among the population during the investigation period.
Conclusions: HCoVs could play a significant role in causing upper respiratory tract infections among adults and older children. Based on the findings of this study and those of others, more extensive studies using other diagnostic methods and higher sample sizes are suggested.
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متن کامل [PDF 470 kb]
(159 دریافت)
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نوع مطالعه: پژوهشي |
موضوع مقاله:
تخصصي
دریافت: 1403/1/17 | پذیرش: 1403/4/19 | انتشار: 1402/4/10
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| ارسال نظر درباره این مقاله |
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Kiani S J, Kachoei Mohaghgh A, Eslami M, Tavakoli A, Karbalaie Niya M H, Javan A, et al . Prevalence of Human Coronaviruses NL63, HKU1, 229E, OC43, MERS, and SARS-CoV-2 among Hospitalized Patients with Acute Respiratory Infection in Tehran. Iran J Virol 2023; 17 (1) :9-14 URL: http://journal.isv.org.ir/article-1-517-fa.html
Prevalence of Human Coronaviruses NL63, HKU1, 229E, OC43, MERS, and SARS-CoV-2 among Hospitalized Patients with Acute Respiratory Infection in Tehran. مجله ویروس شناسی ایران. 1402; 17 (1) :9-14 URL: http://journal.isv.org.ir/article-1-517-fa.html
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