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:: Volume 10, Issue 2 And 3 (9-2016) ::
Iran J Virol 2016, 10(2 And 3): 53-57 Back to browse issues page
Molecular Characterization and Phylogenetic Study of Newcastle Disease Viruses Isolated in Iran, 2014–2015
Mohammad Hadi Kiani, Mohammad Hasan Bozorgmehrifard *, Hossein Hosseini, Saied Charkhkar, Arash Ghalyanchi
Department of Poultry and obstetrics, Science and Research Branch, Islamic Azad University, Tehran, Iran
Abstract:   (3582 Views)
Newcastle disease (ND) is a highly contagious disease that affects many species of birds and causes significant economic losses to the poultry industry worldwide and the pathogenicity of Newcastle disease virus (NDV) strains varies with different virulence. Samples were collected from chicken commercial farms in Iran during 2014–2015. ND virus were characterized (NDV) by partial sequences of fusion genome and compared with other NDV sequences. All viruses showed the amino acid sequence 112 RRQKRF117 at the C-terminus of the F2 protein and phenylalanine at the N-terminus of the F1 protein, residue 117. These amino acid sequences were identical to a known virulent motif. Based on the phylogenetic analysis the Iranian ND isolates are closely related to the genotype VIId of class II NDV strains. The result show that the genotype VIId is dominant and circulating among chicken farms and cause clinical disease.
Keywords: Newcastle disease virus, poultry industry, phylogenetic analysis
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Type of Study: Short communication | Subject: General
Received: 2017/02/4 | Accepted: 2017/07/29 | Published: 2017/07/29
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Kiani M H, Bozorgmehrifard M H, Hosseini H, Charkhkar S, Ghalyanchi A. Molecular Characterization and Phylogenetic Study of Newcastle Disease Viruses Isolated in Iran, 2014–2015. Iran J Virol 2016; 10 (2 and 3) :53-57
URL: http://journal.isv.org.ir/article-1-262-en.html


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Volume 10, Issue 2 And 3 (9-2016) Back to browse issues page
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