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Iran J Virol 2017, 11(3): 33-40 Back to browse issues page
Challenges and Perspectives towards the Development of more Effective Influenza Vaccine
Maryam Ahmadi, Shahla Shahsavandi *
Razi Vaccine & Serum Research Institute
Abstract:   (2325 Views)
Influenza viruses continue to be a major health threat in human and bird populations. The improvements in formulation and production level of the current influenza vaccines are not sufficient to afford complete protection. The continuous antigenic drifts and emergence of endemic and zoonotic strains make influenza vaccine planning difficult. Concern about the emergence of new influenza pandemic provides subject for developing a universal influenza vaccine to be most effective in preventing influenza A either by targeting the HA or other viral proteins. The recombinant and synthetic antigens used in influenza vaccine research and development are generally less immunogenic and need to incorporate novel adjuvants with modified delivery carriers to develop broad-protective vaccines.
Keywords: Influenza virus, vaccine, adjuvant, delivery system
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Type of Study: Review article | Subject: General
Received: 2018/02/3 | Accepted: 2018/08/19 | Published: 2018/08/19
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Ahmadi M, Shahsavandi S. Challenges and Perspectives towards the Development of more Effective Influenza Vaccine. Iran J Virol 2017; 11 (3) :33-40
URL: http://journal.isv.org.ir/article-1-321-en.html

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