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:: Volume 12, Issue 1 (6-2018) ::
Iran J Virol 2018, 12(1): 25-31 Back to browse issues page
The Difference in Levels of Cytomegalovirus Antibodies Among Women in Gestation Age
Zahra Shayesteh , Shaghayegh Yazdani , Hossein Vazeh , Mohammad Farahmabd , Alireza Shokouhifar , Leila Beikzadeh *
Department of Microbiology ,School of allied medical sciences, Alborz university of medical sciences, Karaj, Iran
Abstract:   (2513 Views)
Background and Aims: Congenital cytomegalovirus (CMV) infection is one of the most common viral causes of congenital infection in different areas, and a leading cause of hearing impairment and a contributor to neurodevelopmental disablement in children. Reactivations and reinfections may occur conventionally in the herpes virus family group with the capacity to establish perennial latency in the host.
Materials and Methods: Through a cross-sectional study design, we studied fertile women in a public primary health care center in Karaj city in 1396. In this study, 360 volunteers from women of childbearing age were selected randomly. Then, 5 ml of blood was taken and after serum separation through centrifugation, the serums were frozen at -20°C for further ELISA test. The serums  were  examined for anti-CMV IgG and IgM antibodies.
Results: The results showed that 77% of the subjects (280 out of 360) had CMV infection and none of the participants had CMV-IgM antibodies. There was no significant difference between the educational levels, the age group of 30 and under 30 years of age and the infection rate with CMV.
Conclusions: The results of the present study on the high prevalence of positive CMV IgG antibodies were compatible with the results of other studies performed in Iran and elsewhere in the world indicating the previous confrontation of the individuals with cytomegalovirus and the widespread dissemination of this infection in the community.
Keywords: CMV, Cytomegalovirus, IgG antibodies, Childbearing age
Full-Text [PDF 599 kb]   (1556 Downloads)    
Type of Study: Original article | Subject: Special
Received: 2018/09/16 | Accepted: 2019/10/5 | Published: 2019/10/5
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shayesteh Z, Yazdani S, Vazeh H, Farahmabd M, Shokouhifar A, beikzadeh L. The Difference in Levels of Cytomegalovirus Antibodies Among Women in Gestation Age. Iran J Virol 2018; 12 (1) :25-31
URL: http://journal.isv.org.ir/article-1-333-en.html

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