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جلد 15 شماره 1 صفحات 26-31 برگشت به فهرست نسخه ها
Serological Monitoring of an H5 Inactivated Vaccine in Layer Farms, Iran, 2018
چکیده:   (85 مشاهده)
Background and Aims: Avian influenza (AI) is an acute infectious disease of poultry, waterfowl, wild birds, and animals, zoonotically transmitted to humans. Some incidents of HPAI are reported in Iran: H5N1 and H5N8. Iranian Veterinary Organization decides on vaccination (H5) of layer and breeder flocks in high-risk provinces following the outbreak in Iran. This study aimed to evaluate the serum response of the vaccine in the layer flocks of high-risk provinces.
Materials and Methods: Ten laying farms (Size: 30000-50000) were selected from Qazvin (no: 2) and Isfahan (no: 8) provinces that received the H5 vaccine (Four farms: 1 time; 6 farms: 2 times of vaccine shots). Twenty-five blood samples were taken from each flock. The HI test was carried out in a U-bottomed microtiter plate and 4 HA units of homologous antigen.
Results: The mean titers of antibodies in the poultry farms that received the vaccine once were 1.87, while those that received the immunization twice were 4.90 (significant difference; p<0.05). Also, if we consider protection baseline 4, 4 out of 6 flocks (~67%) could make it above it. Injection of the vaccine twice also improved CV.
Conclusion: In combination with other control measures such as good biosecurity and monitoring programs, vaccination is considered a suitable and powerful tool to support AI eradication or control programs in endemically infected countries if the Iranian Veterinary Organization (IVO) did regular post-vaccination surveillance and evaluated the flocks for silent infections.
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نوع مطالعه: پژوهشي | موضوع مقاله: تخصصي
دریافت: 1399/6/26 | پذیرش: 1400/4/13 | انتشار: 1400/3/30
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Hosseini H, Fallah Mehrabadi M H, Tolooe Zarrin A, Haghbin Nazarpak H, Khaltabadi Farahani R, Abbasian S, et al . Serological Monitoring of an H5 Inactivated Vaccine in Layer Farms, Iran, 2018. Iran J Virol. 2021; 15 (1) :26-31
URL: http://journal.isv.org.ir/article-1-407-fa.html

Serological Monitoring of an H5 Inactivated Vaccine in Layer Farms, Iran, 2018. مجله ویروس شناسی ایران. 1400; 15 (1) :26-31

URL: http://journal.isv.org.ir/article-1-407-fa.html



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دوره 15، شماره 1 - ( 3-1400 ) برگشت به فهرست نسخه ها
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