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Showing 1 results for Behzadifar
Zahra Ghandehari, Omid Salahi Ardekani, Behnaz Hammami, Mahya Arabi, Morteza Rajabi, Sara Shivaei, Alireza Etrati Kooshali, Melina Molaeian, Mohammad Mehdi Fazeli, Fateme Nurzad, Arash Letafati, Mohammad Mahdi Behzadifar, Sheida Sarrafzadeh, Mehdi Norouzi,
Volume 17, Issue 1 (7-2023)
Abstract
Abstract
Background and Aims: COVID-19 is a viral disease that spreads easily, caused by the SARS-CoV-2 virus. This illness has led to a worldwide pandemic and has caused many human fatalities. Patients with cancer have a weakened immune system, which makes them more susceptible to various infections. In this research, we wanted to compare mortality, hospitalization rate, and clinical findings in multiple myeloma (MM) patients.
Materials and Methods: This research examined the effect of COVID-19 on sixteen individuals diagnosed with MM. Four hospitals—Imam Khomeini, Rouhani, Shariati, and Sina—were included in the study. All participants in affiliated hospitals underwent Real-time PCR testing to determine whether they had a viral infection with SARS-CoV-2. According to Iranian CDC guidelines, the real-time reverse transcription-polymerase chain reaction (RT-PCR) test was performed on throat specimens using flocked swabs obtained immediately upon admission to confirm SARS-CoV-2 infection. Collaborative clinical virology necessitates the utilization of two pairs of primers, each designed to target two specific genes (the E gene and the RdRP gene).
Results: Patients with MM were found to have a considerably higher risk of hospitalization and mortality from COVID-19, as per the study results. Common symptoms observed in MM patients with COVID-19 included fever (87.5%), cough (87.5%), and dyspnea (62.5%). Moreover, the study revealed a substantial 17-fold increase in the odds of MM patients with COVID-19 positive compared to their counterparts without COVID-19.
Conclusion: The study results emphasize the critical significance of prompt identification of COVID-19 among patients with MM. It underscores the importance of implementing public health measures, vaccination efforts, and continued research to effectively prevent severe illness and fatalities related to COVID-19 within this vulnerable population.
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