[Home ] [Archive]    
:: Main :: About :: Current Issue :: Archive :: Search :: Contact ::
Main Menu
Journal Information::
Articles archive::
For Authors::
For Reviewers::
Contact us::
Site Facilities::
Medical Journalism::
Search in website

Advanced Search

:: Volume 14, Issue 2 (12-2020) ::
Iran J Virol 2020, 14(2): 29-37 Back to browse issues page
Phylogenetic Study of the Recent Outbreak of Avian Influenza H5 Subtype in Turkeys of East Azerbaijan in 2018
Mohammad Hossein Fallah Mehrabadi , A Hojabr Rajenoni , Hossein Hosseini , Seyed Ali Ghafouri , Naser Sadri , Zahra Ziafati Kafi , Shabnam Aghajantabar , Amir Modiri Hamedan , A Tolooe , H Haghbin Nazarpak , K Parvandar Asadollahi , Arash Ghalyanchilangeroudi *
Department of Microbiology and Immunology, University of Tehran, Faculty of Veterinary Medicine, Tehran, Iran.
Abstract:   (2437 Views)
Background and Aims: Global epizootic distribution of HPAI H5N8 (Clade in poultry and wild birds was demonstrated after 2010. HPAI virus is a major concern in the birds and poultry industry and global human health. Wild migratory birds and their link to backyard birds play a critical role in spreading HPAI and creating genetic reassortment.
Materials and Methods: In this study in 2018, HPAI H5N8 was isolated from Backyard poultry (turkey) in East Azerbaijan Province, Iran. Three reports of outbreaks were submitted. The first outbreak was in a village, Sholebaran, and the second was in a Livestock market in Bahman, and the third was in another Village, Yaghbastloo. Tracheal and pancreas tissue samples were obtained from 10 dead birds, and 300 susceptible domestic birds include in the turkey and chickens. Samples' diagnosis was based on real-time reverse transcriptase PCR (RRT-PCR) and partial HA gene sequencing. Turkey samples were positive and characterized as H5N8.
Results: Phylogenetic analysis result based on a partial HA gene revealed that the Iranian HPAI H5N8 virus in our study, belong to the subgroup clade and cluster within group B.
Conclusion: These findings indicate that it provides new insights into the evolution and spread of H5N8 in Iran; based on these results, we have to recognize an improper monitoring protocol for reducing the reassortment of them. Therefore, we could prevent HPAI from circulating.
Keywords: Phylogenetic tree, H5N8, Avian influenza, Backyard poultry, HAPI, Iran
Full-Text [PDF 762 kb]   (1569 Downloads)    
Type of Study: Original article | Subject: Special
Received: 2020/09/16 | Accepted: 2020/12/20 | Published: 2020/12/20
Send email to the article author

Add your comments about this article
Your username or Email:


XML     Print

Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:

Fallah Mehrabadi M H, Hojabr Rajenoni A, Hosseini H, Ghafouri S A, Sadri N, Ziafati Kafi Z, et al . Phylogenetic Study of the Recent Outbreak of Avian Influenza H5 Subtype in Turkeys of East Azerbaijan in 2018. Iran J Virol 2020; 14 (2) :29-37
URL: http://journal.isv.org.ir/article-1-406-en.html

Rights and permissions
Creative Commons License This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
Volume 14, Issue 2 (12-2020) Back to browse issues page
Persian site map - English site map - Created in 0.04 seconds with 39 queries by YEKTAWEB 4639