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:: Volume 10, Issue 2 And 3 (9-2016) ::
Iran J Virol 2016, 10(2 And 3): 13-18 Back to browse issues page
Evaluation of anti-hepatitis E virus antibody among hemodialysis patients in Gorgan, north of Iran
Hamed Naziri Mr, Alireza Tahamtan Mr, Abdolvahab Moradi Dr, Alijan Tabarraei Dr
PhD 2. Department of Microbiology, School of Medicine, Golestan University of Medical Sciences, Gorgan, Iran
Abstract:   (607 Views)
Background and Aims: Hepatitis E virus is a public health concern and about a third of people in the world live in endemic areas. Although HEV is believed to be transmitted by fecal-oral routes between humans in low sanitary conditions, but evidence of transmission have been reported in hemodialysis (HD) patients.
Materials and Methods: Aim of present study was to determine the prevalence of anti-HEV antibody among HD patients in Gorgan, north of Iran. In this cross-sectional study, totally 300 HD patients from May to December 2014 were tested for detection of anti-HEV IgG and IgM by commercial HEV enzyme-linked immunosorbent assay (ELISA) kit. Demographic variables were collected in pre-designed questionnaires.
Results: Out of 300 individuals, 148 (49.3%) were male and 152 (50.7%) were female. The overall anti-HEV IgG seroprevalence rate was 4%. Result showed significant association between anti-HEV IgG and duration of dialysis (p = 0.03), but there were no significant differences between the subjects grouped according to gender, Ethnicity, dialysis per week and age. No anti-HEV IgM were detected in patients.
Conclusions: Since our finding showed statically significant relationship between duration of hemodialysis and anti-HEV. Therefore, hemodialysis maybe be considered as a risk factor in HEV transmission. However further studies are needed to confirm our data.
Keywords: HEV, Hemodialysis, Seroprevalence, Iran
Full-Text [PDF 248 kb]   (144 Downloads)    
Type of Study: Original article | Subject: General
Received: 2017/02/25 | Accepted: 2017/07/29 | Published: 2017/07/29
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Naziri H, Tahamtan A, Moradi A, Tabarraei A. Evaluation of anti-hepatitis E virus antibody among hemodialysis patients in Gorgan, north of Iran. Iran J Virol. 2016; 10 (2 and 3) :13-18
URL: http://journal.isv.org.ir/article-1-267-en.html


Volume 10, Issue 2 And 3 (9-2016) Back to browse issues page
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