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:: Volume 10, Number 2 and 3 (9-2016) ::
Iran J Virol 2016, 10(2 and 3): 13-18 Back to browse issues page
Evaluation of anti-hepatitis E virus antibody among hemodialysis patients in Gorgan, north of Iran
Mr Hamed Naziri, Mr Alireza Tahamtan, Dr Abdolvahab Moradi, Dr Alijan Tabarraei *
PhD 2. Department of Microbiology, School of Medicine, Golestan University of Medical Sciences, Gorgan, Iran
Abstract:   (273 Views)
Background and Aims: Hepatitis E virus is a public health concern and about a third of people in the world live in endemic areas. Although HEV is believed to be transmitted by fecal-oral routes between humans in low sanitary conditions, but evidence of transmission have been reported in hemodialysis (HD) patients.
Materials and Methods: Aim of present study was to determine the prevalence of anti-HEV antibody among HD patients in Gorgan, north of Iran. In this cross-sectional study, totally 300 HD patients from May to December 2014 were tested for detection of anti-HEV IgG and IgM by commercial HEV enzyme-linked immunosorbent assay (ELISA) kit. Demographic variables were collected in pre-designed questionnaires.
Results: Out of 300 individuals, 148 (49.3%) were male and 152 (50.7%) were female. The overall anti-HEV IgG seroprevalence rate was 4%. Result showed significant association between anti-HEV IgG and duration of dialysis (p = 0.03), but there were no significant differences between the subjects grouped according to gender, Ethnicity, dialysis per week and age. No anti-HEV IgM were detected in patients.
Conclusions: Since our finding showed statically significant relationship between duration of hemodialysis and anti-HEV. Therefore, hemodialysis maybe be considered as a risk factor in HEV transmission. However further studies are needed to confirm our data.
Keywords: HEV, Hemodialysis, Seroprevalence, Iran
Full-Text [PDF 248 kb]   (83 Downloads)    
Type of Study: Original article | Subject: General
Received: 2017/02/25 | Accepted: 2017/07/29 | Published: 2017/07/29
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Naziri H, Tahamtan A, Moradi A, Tabarraei A. Evaluation of anti-hepatitis E virus antibody among hemodialysis patients in Gorgan, north of Iran. Iran J Virol. 2016; 10 (2 and 3) :13-18
URL: http://journal.isv.org.ir/article-1-267-en.html
Volume 10, Number 2 and 3 (9-2016) Back to browse issues page
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