[Home ] [Archive]    
:: Main :: About :: Current Issue :: Archive :: Search :: Submit :: Contact ::
:: Volume 1, Issue 4 (11-2007) ::
Iran J Virol 2007, 1(4): 17-22 Back to browse issues page
Hepatitis C virus infection and genotypes in blood donors
Z Sharifi , M Mahmoudian Shooshtari
Assistant professor of Research center, Iranian Blood Transfusion Organization (IBTO), Tehran, Iran.
Abstract:   (2793 Views)

Abstract: Genotyping of the hepatitis C virus (HCV) is important for designing therapeutic strategies and regional specific diagnostic assays. The aim of this study was to identify the HCV genotypes in HCV infected blood donors. This is the first report on HCV genotypes in blood donors in Iran. In this cross-sectional study, 103 blood donors with hepatitis C were investigated for HCV genotypes. HCV genotyping was carried out using type-specific primers from the core region of the viral genome. From 103 blood donors, only96 cases had genotypes which could be typed. The highest frequency genotype 1a, with 53 (51.5%) of subjects. Genotype 3a and 1b were the other frequent genotypes with 39 (37.9 %) and 4 (3.9%)   subjects, respec-tively. These results indicate that the dominant HCV genotypes among blood donors were 1a, 3a and 1b respectively. It was also noticed that more of the blood donors infected with genotypes 1a and 3a had history of intravenous drug abuse and tattooing.

Keywords: HCV, genotypes, blood donors, Iran
Full-Text [PDF 224 kb]   (555 Downloads)    
Subject: Special
Received: 2016/08/27 | Accepted: 2016/08/27 | Published: 2016/08/27
Send email to the article author

Add your comments about this article
Your username or Email:

CAPTCHA



XML     Print


Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:

Sharifi Z, Mahmoudian Shooshtari M. Hepatitis C virus infection and genotypes in blood donors. Iran J Virol. 2007; 1 (4) :17-22
URL: http://journal.isv.org.ir/article-1-212-en.html


Rights and permissions
Creative Commons License This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
Volume 1, Issue 4 (11-2007) Back to browse issues page
Persian site map - English site map - Created in 0.04 seconds with 29 queries by YEKTAWEB 4331