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:: Volume 10, Issue 4 (12-2016) ::
Iran J Virol 2016, 10(4): 18-25 Back to browse issues page
Full-length Characterization of S1 Gene of Iranian QX Avian Infectious Bronchitis Virus Isolates, 2015
Homayoon Davam , Arash Ghalyanchi langeroudi , Masoud Hashemzadeh , Vahid Karimi , Taha Zabihi , Waleed Seger , Hamideh Najafi
Department of Research and Production of Poultry Viral Vaccine, Razi Vaccine and Serum Research Institute, Karaj, Iran
Abstract:   (1007 Views)
Background and Aims: Avian infectious bronchitis (IB) has prevalent in the most chicken farms during recent years, in spite of the IB vaccination program which has been widely performed in Iran. To better understand the molecular epidemiology of IBV in Iran, the full length sequences of S1 gene of Iranian QX IBVs were determined and phylogenetic analysis was done using some sequences of IBV.
Materials and Methods: To better understand the molecular epidemiology of IBV in Iran, the full length sequences of S1 gene of Iranian QX IBVs were determined and phylogenetic analysis was done using some sequences of IBV.
Results: Iranian QX IBVs were located in LX4 (Cluster 2). The nucleotides homologies were 99.52% - 100% between the isolates. Phylogenetic analysis revealed that all the IBV isolates were very similar and probably had a common origin. The hyperactive variable regions of S1 were determined.
Conclusions: The results from this study and other published results in the GenBank database showed that the isolates circulating in Iran in recent years were mainly LX4 (Cluster 2) genotype, which is the predominant genotype circulating in Iran in recent years (After first report of QX IBV in Iran, 2011). This finding provides important information on IBV evolution in Iran.
Keywords: Avian Infectious Bronchitis, QX, Iran, Phylogenetic analysis, Spike
Full-Text [PDF 1101 kb]   (343 Downloads)    
Type of Study: Original article | Subject: General
Received: 2017/04/24 | Accepted: 2017/10/14 | Published: 2017/10/14
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Davam H, Ghalyanchi langeroudi A, Hashemzadeh M, Karimi V, Zabihi T, Seger W et al . Full-length Characterization of S1 Gene of Iranian QX Avian Infectious Bronchitis Virus Isolates, 2015 . Iran J Virol. 2016; 10 (4) :18-25
URL: http://journal.isv.org.ir/article-1-272-en.html


Volume 10, Issue 4 (12-2016) Back to browse issues page
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