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Detection of Respiratory Viruses in Children Less than 5 Years of Age with Suspected COVID-19 Infection in East Azerbaijan Iran
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Moslem Ghaseminia   , Vahdat Poortahmasebi , Arezou Azadi , Hossein Bannazadeh Baghi , Mahin Ahangar Oskouee *  |
| Infectious and Tropical Diseases Research Center,& Department of Microbiology & Virology, Faculty of Medicine, Tabriz University of Medical Sciences, Tabriz, Iran |
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Abstract: (100 Views) |
| Abstract
Background and Aims: Coronaviruses are one of the most common viral agents associated with respiratory disease in children, causing severe respiratory infections and hospitalizations in children. However, there is no information about the prevalence of these seasonal coronavirus infection in the northwest of Iran. The aim of this study was to identify and investigate the frequency of NL63, OC-43 and 229E, Influenza type A, B viruses in children less than 5 years of age with respiratory infection in the northwest of Iran during the COVID-19 pandemic.
Material& Method: In the present study, 164 respiratory samples were taken from children with respiratory problems who were negative for influenza type A, B and SARS-CoV-2 (Taqman Real Time RT-PCR method). NL63, OC-43 and 229E viruses were evaluated in a panel by Cyber green RT-PCR method.
Results: In our investigation, 2 out of 164 (1.2%) cases of NL63 infection were detected in children less than one year, but OC-43 and 229E viruses were not detected. NL63 positive samples in this study were detected in late winter and early spring.
Conclusion: Considering the role of this virus in causing respiratory problems in children and immunocompromised patients, identification and diagnosis of these pathogens in respiratory samples is important. Paying attention to viral infections in the northwest of Iran can play an important role in improving the management of infectious agents in this area.
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| Keywords: Coronaviruses, SARS-CoV-2, HCoV-NL-63, HCoV-OC-43, HCoV-229E, Acute Respiratory Tract Infections (ARTI) |
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Full-Text [PDF 571 kb]
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Type of Study: Original article |
Subject:
Special
Received: 2023/04/8 | Accepted: 2023/12/22 | Published: 2023/07/10
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